Emerging Nanocarrier Strategies for Precision Drug Delivery in Cancer Treatment: Innovations and Therapeutic Implications

Micheal Abimbola Oladosu; Moses Adondua Abah; Lawal Mahmud; Philip Oluwajimisore Olowe; Mahmud Seyi Abdurrahman; Kannolu Millie Ebenebe; Faridah Mobolanle Banwo; Oladapo Abiola Balogun; Anthony Olalekan Akande; Dominic Agida Ochuele; Olaide Ayokunmi Oladosu

doi:10.5455/JCRR.2026.v3.i1.4

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J Cancer Res Rev. 2026; 3(1): 56-65

doi: 10.5455/JCRR.2026.v3.i1.4

Emerging Nanocarrier Strategies for Precision Drug Delivery in Cancer Treatment: Innovations and Therapeutic Implications

Micheal Abimbola Oladosu, Moses Adondua Abah, Lawal Mahmud, Philip Oluwajimisore Olowe, Mahmud Seyi Abdurrahman, Kannolu Millie Ebenebe, Faridah Mobolanle Banwo, Oladapo Abiola Balogun, Anthony Olalekan Akande, Dominic Agida Ochuele, Olaide Ayokunmi Oladosu.

Abstract
Abstract:
Conventional chemotherapeutics are frequently limited by systemic toxicity and poor selectivity, and cancer continues to be a leading cause of death globally. With specially designed nanocarriers that transport medications straight to tumor locations, nanotechnology provides encouraging alternatives. The development of tailored drug delivery systems has increased due to the drawbacks of traditional cancer therapies, including multidrug resistance, systemic toxicity, and nonspecific drug distribution. By increasing site-specific drug accumulation, reducing off-target effects, and boosting therapeutic efficacy, nanocarrier-based delivery presents a possible option. Recent developments in nanocarrier systems—such as liposomes, dendrimers, solid lipid nanoparticles, and polymeric micelles—that are intended for the accurate administration of chemotherapeutic drugs are highlighted in this study. This systematic review synthesizes recent advancements (2018–2025) in nanocarrier strategies, exploring diverse types, their mechanisms of action, and their applications in targeted drug delivery. Important topics covered include targeted ligands, controlled release methods, drug encapsulation effectiveness, and physicochemical characteristics. The study also examines preclinical and clinical research that shows how nanocarriers can be used to treat different kinds of cancer. Large-scale production, regulatory restrictions, and immunological clearance are still issues despite significant advancements. In order to maximize therapeutic results, future developments will focus on integrating biosensors, artificial intelligence, and stimuli-responsive systems. Our results demonstrate developments in polymeric nanoparticles, dendrimers, liposomes, and hybrid systems. In order to expedite the clinical translation of nanomedicine in oncology, this review promotes a multidisciplinary strategy.

Key words: Nanocarriers; Drug delivery; Cancer therapy; Tumor targeting; Liposomes.

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How to Cite this Article

Pubmed Style

Oladosu MA, Abah MA, Mahmud L, Olowe PO, Abdurrahman MS, Ebenebe KM, Banwo FM, Balogun OA, Akande AO, Ochuele DA, Oladosu OA. Emerging Nanocarrier Strategies for Precision Drug Delivery in Cancer Treatment: Innovations and Therapeutic Implications. J Cancer Res Rev. 2026; 3(1): 56-65. doi:10.5455/JCRR.2026.v3.i1.4

Web Style

Oladosu MA, Abah MA, Mahmud L, Olowe PO, Abdurrahman MS, Ebenebe KM, Banwo FM, Balogun OA, Akande AO, Ochuele DA, Oladosu OA. Emerging Nanocarrier Strategies for Precision Drug Delivery in Cancer Treatment: Innovations and Therapeutic Implications. https://www.jcrronline.org//?mno=274964 [Access: April 01, 2026]. doi:10.5455/JCRR.2026.v3.i1.4

AMA (American Medical Association) Style

Oladosu MA, Abah MA, Mahmud L, Olowe PO, Abdurrahman MS, Ebenebe KM, Banwo FM, Balogun OA, Akande AO, Ochuele DA, Oladosu OA. Emerging Nanocarrier Strategies for Precision Drug Delivery in Cancer Treatment: Innovations and Therapeutic Implications. J Cancer Res Rev. 2026; 3(1): 56-65. doi:10.5455/JCRR.2026.v3.i1.4

Vancouver/ICMJE Style

Oladosu MA, Abah MA, Mahmud L, Olowe PO, Abdurrahman MS, Ebenebe KM, Banwo FM, Balogun OA, Akande AO, Ochuele DA, Oladosu OA. Emerging Nanocarrier Strategies for Precision Drug Delivery in Cancer Treatment: Innovations and Therapeutic Implications. J Cancer Res Rev. (2026), [cited April 01, 2026]; 3(1): 56-65. doi:10.5455/JCRR.2026.v3.i1.4

Harvard Style

Oladosu, M. A., Abah, . M. A., Mahmud, . L., Olowe, . P. O., Abdurrahman, . M. S., Ebenebe, . K. M., Banwo, . F. M., Balogun, . O. A., Akande, . A. O., Ochuele, . D. A. & Oladosu, . O. A. (2026) Emerging Nanocarrier Strategies for Precision Drug Delivery in Cancer Treatment: Innovations and Therapeutic Implications. J Cancer Res Rev, 3 (1), 56-65. doi:10.5455/JCRR.2026.v3.i1.4

Turabian Style

Oladosu, Micheal Abimbola, Moses Adondua Abah, Lawal Mahmud, Philip Oluwajimisore Olowe, Mahmud Seyi Abdurrahman, Kannolu Millie Ebenebe, Faridah Mobolanle Banwo, Oladapo Abiola Balogun, Anthony Olalekan Akande, Dominic Agida Ochuele, and Olaide Ayokunmi Oladosu. 2026. Emerging Nanocarrier Strategies for Precision Drug Delivery in Cancer Treatment: Innovations and Therapeutic Implications. Journal of Cancer Research and Reviews, 3 (1), 56-65. doi:10.5455/JCRR.2026.v3.i1.4

Chicago Style

Oladosu, Micheal Abimbola, Moses Adondua Abah, Lawal Mahmud, Philip Oluwajimisore Olowe, Mahmud Seyi Abdurrahman, Kannolu Millie Ebenebe, Faridah Mobolanle Banwo, Oladapo Abiola Balogun, Anthony Olalekan Akande, Dominic Agida Ochuele, and Olaide Ayokunmi Oladosu. "Emerging Nanocarrier Strategies for Precision Drug Delivery in Cancer Treatment: Innovations and Therapeutic Implications." Journal of Cancer Research and Reviews 3 (2026), 56-65. doi:10.5455/JCRR.2026.v3.i1.4

MLA (The Modern Language Association) Style

Oladosu, Micheal Abimbola, Moses Adondua Abah, Lawal Mahmud, Philip Oluwajimisore Olowe, Mahmud Seyi Abdurrahman, Kannolu Millie Ebenebe, Faridah Mobolanle Banwo, Oladapo Abiola Balogun, Anthony Olalekan Akande, Dominic Agida Ochuele, and Olaide Ayokunmi Oladosu. "Emerging Nanocarrier Strategies for Precision Drug Delivery in Cancer Treatment: Innovations and Therapeutic Implications." Journal of Cancer Research and Reviews 3.1 (2026), 56-65. Print. doi:10.5455/JCRR.2026.v3.i1.4

APA (American Psychological Association) Style

Oladosu, M. A., Abah, . M. A., Mahmud, . L., Olowe, . P. O., Abdurrahman, . M. S., Ebenebe, . K. M., Banwo, . F. M., Balogun, . O. A., Akande, . A. O., Ochuele, . D. A. & Oladosu, . O. A. (2026) Emerging Nanocarrier Strategies for Precision Drug Delivery in Cancer Treatment: Innovations and Therapeutic Implications. Journal of Cancer Research and Reviews, 3 (1), 56-65. doi:10.5455/JCRR.2026.v3.i1.4

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